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Cyclophilin inhibitor C31
CAS No. ——
Cyclophilin inhibitor C31 ( SMCypI C31 )
产品货号. M17086 CAS No. ——
Cyclophilin inhibitor C31 (SMCypI C31) is a small-molecule cyclophilin (CypA) inhibitor (SMCypI) with PPIase inhibition IC50 of 0.1 uM.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 100MG | 获取报价 | 有现货 |
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| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Cyclophilin inhibitor C31
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述Cyclophilin inhibitor C31 (SMCypI C31) is a small-molecule cyclophilin (CypA) inhibitor (SMCypI) with PPIase inhibition IC50 of 0.1 uM.
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产品描述Cyclophilin inhibitor C31 (SMCypI C31) is a small-molecule cyclophilin (CypA) inhibitor (SMCypI) with PPIase inhibition IC50 of 0.1 uM, displays anti-HCV activity (HCV Gt1b replicon EC50=0.4 uM) and disrupts the CypA-NS5A interaction; exerts at least additive antiviral effects when combined with the NS5A inhibitor ledipasvir and is fully active against ledipasvir-resistant viruses; also inhibits the replication of other members of the Flaviviridae family (DENV EC50=7.3 uM), YFV EC50, 27.2 uM, and ZIKV EC50=48.0 uM), without significant cytotoxicity.
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同义词SMCypI C31
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通路Microbiology/Virology
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靶点HCV
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受体HCV
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研究领域——
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适应症——
化学信息
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CAS Number——
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分子量474.62
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分子式C27H30N4O2S
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纯度>98% (HPLC)
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溶解度——
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SMILES——
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化学全称1-(4-aminobenzyl)-3-(2-(2-(2-(methylthio)phenyl)pyrrolidin-1-yl)-2-oxo-1-phenylethyl)urea
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Nevers Q, et al. Antimicrob Agents Chemother. 2018 Jun 26;62(7). pii: e00126-18.
产品手册
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